Moyamoya Disease Treatments can be Evaluated Using SPECT Blood Flow Imaging

Moyamoya Disease SPECT Imaging post surgery (click here to see article)

Clin Nucl Med. 2017 May;42(5):e269-e272. doi: 10.1097/RLU.0000000000001606.

Brain Perfusion Before and After Surgical Treatment of Moyamoya Disease.


Moyamoya disease is characterized by bilateral progressive terminal internal carotid arteries steno-occlusion. In this patient, the disease affected middle cerebral arteries and was disclosed after a left frontal cerebral infarction. Brain HMPAO perfusion scintigraphy with acetazolamide challenge, obtained before surgical treatment, demonstrates an extended bilateral frontal hypoperfusion with a vascular steal phenomenon. The same examination obtained after surgical treatment demonstrates a frank improvement in basal brain vascularization, with nearly complete correction of vascular steal phenomenon. HMPAO brain scintigraphy is a very useful tool in the assessment of moyamoya disease severity before surgery and for the evaluation of treatment efficiency


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